褶合曲线分析法同时测定头孢哌酮钠舒巴坦钠注射剂中两组分的含量

Simultaneous determination of two components in the compound Cefoperazone Sodium and Sulbactam Sodium injection by convolution curve method

目的:采用褶合曲线分析法不经分离同时测定头孢哌酮钠舒巴坦钠注射剂中哌酮钠和舒巴坦钠二组分的含量。方法:以褶合光谱为基础,利用计算机信息处理技术的褶合曲线分析法。结果:头孢哌酮钠舒巴坦钠注射剂中哌酮钠和舒巴坦钠二组分的平均回收率和相对标准偏差(RSD)分别是99.71%,1.33%;100.05%,0.28%。结论:该方法用于头孢哌酮钠舒巴坦钠注射剂中两组分含量的测定,既简便,又快速,准确度较高。

Objective： To simultaneous determination of two main components in the compound Cefoperazone Sodium and Sulbactam Sodium injection without the separation of the compound. Methods： The convolution spectrometry of computer information process technology was used, based on convolution spectrometry. Result： The mean recoveries and RSD of Cefoperazone Sodium and Sulbactam Sodium were 99. 71%, 1.33 % and 100. 05%, 0. 28 %, respectively. Conclusion ： The method is used for simultaneous determination of two components in the compound Cefoperazone Sodium and Sulhactam Sodium injection. The method was simple, rapid and accuracy.