心绞痛患者AMI后的临床研究

Clinical anaysis of patieats with angina pectoris before AMI

目的了解缺血预适应IP对AMI(急性心肌梗死)患者心脏的保护作用。方法84例AMI患者分为有梗死前心绞痛(AP)组35例和无梗死前心绞痛(NAP)组49例进行临床资料的对比分析。结果心功能KillapⅢ～Ⅳ者AP组5例(14.29)%,NAP组22例(44.9%),x2=8.77,P<0.01;短阵室速;AP组5例(14.29%),NAP组17例(34.69%),x2=4.398,P<0.05;室速+室颤;AP组2例(5.7%),NAP组11例(22.45%),x2=4.37,P<0.05;住院病死率;AP组2例(5.7%)NAP组11例(22.45%),x2=4.37,P<0.05;两组比较有显著性差异。结论人类初次心肌梗死前心绞痛反复发作,对人类心脏具有IP保护作用,可改善心功能,减少室性心律失常的发生,降低住院病死率。

Objective To investigate the protective effect of ischemic precorditioning （IP） in patients with acute myocardial infarction （AMI）. Methods Analyze the clinical data of 84 patients with AMI, in which 35 cases suffered with angina pectofis before AMI, and 49 cases without angina peetofis（NAP） before AMI. Results Cardiac funeation Killip Ⅲ-Ⅳ occurred in 5 eases（14.29%） in the AP group, and 22 eases（44.9%） in NAP group（χ^2=8.77, P〈0.01）; paroxy small ventricular tachycardia was seen in 5 eases （14.29%） in AP group AP, and 17（34.69%） in NAP group （χ^2=4.398, P〈0.05）; ventricular tachycardia and ventricular fibrillation was seen in 2 （5.7%） in NAP group and 11（22.45%） in NAP group（χ^2=4.37, P〈0.05）. Conclusions The occurrence of angina pectoris before AMI can protect the heart by IP, which can improve the patient＇s cardiac fuaction and reduce ventricular arrhythmin and death.