合成酚类抗氧剂1010的新工艺Ⅰ．3，5－二叔丁基－4－羟基苯丙酸甲酯的合成

Synthesis of Tetrakis [3 (3,5 Di Tert Butyl 4 Hydroxyphenyl) Propionyloxymethyl] Methane by a New Method Ⅰ Studies on the Synthesis of Methyl (3,5 Di Tert Butyl 4 Hydroxyphenyl) Propionate

在１５升的不锈钢反应釜中以２，６－二叔丁基苯酚、丙烯酸甲酯为原料，在叔丁醇钾催化剂存在下，对一步法合成抗氧剂１０１０的中间体３，５－二叔丁基－４羟基苯丙酸甲酯的工艺条件进行了研究，优化了反应条件。结果表明，在较佳的条件下，反应的选择性及收率分别超过９８％、９５％。

Methyl (3,5 di tert butyl 4 hydroxyphenyl) propionate,an intermediate for the preparation of tetrakis [3 (3,5 di t butyl 4 hydroxyphenyl) propionyloxymethyl] methane by one step method,was synthesized with 2,6 di tert buty phenol and methyl acrylate in the presence of potassium tert butoxide in a 15 liter stainless batch tank reactor.The optimum technological conditions were determined and excellent yield and selectivity were obtained.