血栓形成过程与其密度的相关性研究

Correlation between thrombosis and density

目的探讨血液凝固过程结构状态改变及其密度变化的相关性。方法采用物理学方法,对新血样标本,取其自然凝结的血栓,对凝血块密度参量变化进行研究。结果在血栓形成过程中,血栓密度伴随血凝块形成时间延长而明显增加,使其密度随血栓凝龄的延长成正相关,反映了血液凝固状态的变化伴有物理参量的明显改变。结论研究表明血栓密度具有随凝龄改变的特征,这对于研究血液凝固结构状态变化,提高血栓超声消溶效果及其临床应用具有参考价值。

Aim To explore the correlation between thrombosis and density change of gores. Methods Using physic methods in new blood samples, the natural thrombus is taken and used the blood bolts of different ages （ gores, flowing out of our bodies in different intervals） is used to calculate the changes of density parameters in the gores. Results During the process of thrombosis, the density of thrombus was increasing obviously along with the gore forming time. That made it positive relationship that density of the clot complied with the prolonging thrombus ageing. It reflected that all the state changes during thrombosis had distinct changes of physical parameters. Conclusion The results showed that thrombus density has the characteristics of the changing with the gore aging. This may also provide reliable evidence that the changes of thrombus structures and densities may improve the effect of intravascular ultrasonic thrombosis ablation and may be beneficial of clinic use.