期刊文献+

肝细胞核因子与肝细胞分化基因调控 被引量:3

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出处 《肝脏》 2006年第3期193-194,共2页 Chinese Hepatology
基金 国家自然科学基金(30200122)
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参考文献16

  • 1Rausa FM, Tan Y, Costa RH. Association between HNF-6 and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding. Mol Cell Biol, 2003, 23: 437-449.
  • 2Lannoy V J, Rodolosse A, Pierreux CE, et al. Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF). J Biol Chem, 2000, 275: 22098-22103.
  • 3Barbacci E, Reber M, Ott MO, et al. Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification. Development, 1999, 126:4795-4805.
  • 4Shen W, Scearce LM, Bresteni JE, et al. Foxa3 (hepatocyte nuclear factor 3 gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. J Biol Chem, 2001, 276: 42812-42817.
  • 5Rausa FM, Tan Y, Zhou H, et al. Elevated levels of HNF-3β in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis. Mol Cell Biol, 2000, 20: 8264-8282.
  • 6Tan Y, Hughes D, Wang X, et al. Adenovirus-mediated increase in HNF-3beta or HNF-3alpha shows differences in levels of liver glycogen and gene expression. Hepatology, 2002, 35: 30-39.
  • 7Hughes DE, Stolz DB, Yu S, et al. Elevated hepatocyte levels of the forkhead box A2 (HNF-3β) transcription factor cause postnatal steatosis and mitochondrial damage. Hepatology, 2003, 37: 1414-1424.
  • 8Watt AJ, Garrison WD, Duncan SA. HNF4: a central regulator of hepatocyte differentiation and function. Hepatology, 2003, 37: 1249-1253.
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同被引文献45

  • 1贺治青,曾欣,林勇,谢渭芬.移植肝细胞增殖与分化的转录调控[J].中华肝脏病杂志,2005,13(9):712-714. 被引量:1
  • 2魏欣,贾战生.肝细胞核因子4在肝细胞分化和成熟中的作用[J].医学分子生物学杂志,2005,2(6):463-466. 被引量:2
  • 3Yin C,Lin Y,Chen YX,et al.Differentiation therapy of hepatocellular in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4a gene.Hepatology,2008,48(5):1528-1539.
  • 4Rausa FM,Tan Y,Costa RH.Association between HNF-6 and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.Mol Cell Biol,2003,23(2):437-449.
  • 5Hertz R,Kalderon B,Byk T,et al.Thioesterase activity and acyl-CoA/fatty acid cross-talk of hepatocyte nuclear factor-4alpha.J Biol Chem,2005,280(26):24451-24461.
  • 6Schrem H,Klempnauer J,Borlak J.Liver-enriched transcription factors in liver function and development Part I:the hepatocyte nuclear factor network and liver-specific gene expression.Pharmacol Rev,2002,54(1):129-158.
  • 7Duncan SA,Manova K,Chen W S,et al.Expression of tran-scription factor HNF-4 in the extraembryonie endoderm gut,and nephrogenic tissue of the developing mouse embryo:HNF-4 is a marker for primary endoderm in the implanting blastocyst.Proc Natl Acad Sci USA,1994,91(16):7598.
  • 8Pantelis Hatzis,Iannis Talianidis.Regulatory mechanisms controlling human hepatocyte nuclear factor 4a gene expression.Molecular And Cellular Biology,Nov,2001:7320-7330.
  • 9Chen WS,Manova K,Weinstein DC,et al.Disruption of the HNF-4 gene,expressed in visceral endoderm,leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.Genes Dev,994,8(20):2466-2477.
  • 10Duncan SA,Nagy A,Chan W.Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm:tetraploid rescue of Hnf-4-/-embryos.Development,1997,124(2):279-87.

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