原发性高血压患者颈动脉病变的临床分析

Clinical analyses on primary hypertension patients' carotid artery lesion

目的:探讨原发性高血压患者颈动脉病变和血压水平、年龄及血脂之间的关系。方法:采用超声检测60例原发性高血压患者和10例健康者的颈动脉内膜中层厚度及斑块大小,同时进行血脂、高血压分级及年龄比较。结果:(1)高血压病患者颈总动脉及颈内动脉内膜中层厚度与高血压分级呈正相关,血压分组越高者,颈动脉内膜增厚越明显;(2)随着年龄的增加,患者颈动脉斑块阳性率增加,不同年龄组之间差异显著;(3)颈动脉内膜增厚组和斑块组与胆固醇、低密度脂蛋白有一定的相关性。结论:高血压患者颈动脉内膜的病变程度受血压水平、年龄及血脂等因素的影响。

Objective To investigate the relationship carotid artery lesion and blood pressure level, age, blood lipids in the patients with primary hypertension. Methods Ultrasound was used to examine their internal membrane intermediate deck thickness and clots size in 60 primary hypertension patients and 10 healthy controls, and blood lipid and hypertension grading, age were compared at the same time. Results ① Hypertension grading was positively related to internal carotid artery intermediate deck thickness in the patients with hypertension. The higher the hypertension grading, the more obviously the carotid artery internal membrane thickening. ② The prevalence of carotid artery clots was increased with aging. The diversity was distinct among different age group. ③ Carotid artery internal membrane group and clot group had positive relation to TC and LDL. Conclusion The serious extent of hypertension patients＇ carotid artery internal membrane lesion is influenced by blood pressure level, aging and blood lipids.