高尿酸血症与高血压发生心血管事件的相关性探讨

Study on the relationship between hyperuricemia and cardiovascular events in hypertension

目的:探讨高尿酸血症与高血压发生心血管事件的相关性。方法:对187例高血压伴高尿酸血症患者,按不同的血压水平(1,2,3级)及心血管事件(心力衰竭、不稳定性心绞痛、急性心肌梗死)分组,分别比较血尿酸的变化。结果:高血压1,2,3级之间血尿酸差异无显著性(P>0.05);高血压伴高尿酸血症发生心血管事件与无心血管事件组相比血尿酸差异有显著性(P<0.05);心血管事件组之间血尿酸差异无显著性(P>0.05)。结论:高尿酸血症与高血压的级别高低无相关性;与高血压发生心血管事件有相关性。

Objective To study the relationship between hyperuricemia and cardiovascular events in hypertension. Methods One hundred and eighty-seven patients with hypertension attendant hyperuricemia were divided in groups according to different blood pressure grades （1, 2, 3 grade） and cardiovascular events （heart failure, unstable angina, acute myocardial infarction）. The changes of serum uric acid were compared in different groups. Results Serum uric acid had no significant difference in hypertension 1, 2, 3 grade groups（P〉0. 05） and in cardiovascular events groups （P〉 0.05）. Serum uric acid had significant difference （P 〈 0. 05） between hypertension attendant hyperuricemia with cardiovascular events group and without cardiovascular events group. Conclusion Hyperuricemia is not related to the grades of hypertension, but is related to cardiovascular events in hypertension.