真武汤对肉鸡腹水综合征的防治作用

The preventive effect of Zhen-Wu-Tang on ascites syndrome of broiler

选用15日龄艾维茵肉仔鸡256只，随机分成C1、C2、Tl、T24个处理组。C1组在常温（18～22℃）环境中饲养，饮水中不添加任何药物，为正常对照组；T1、T2和C2组在低温（8～12℃）环境中饲养。人工复制肉鸡腹水综合征（AS）模型，T1组饮水中按肉鸡体重添加真武汤口服液剂量为0．8mL·kg^-1（中药组）；T2组饮水中添加维生素C和维生素E，剂量分别为0．5g·L^-1和0．1g·L^-1，作为药物预防组（维生素组），用药期均为20d；C2组饮水中不添加任何药物，为模型对照组，以探讨真武汤口服液对肉鸡AS的预防效果。结果表明：整个试验期间．T1、C1组腹水发病率极显著低于C2组（P〈0．01），T2组腹水发病率显著低于C2组（P〈0．05），T1、C1组发病率最低，为3．13％，C2组发病率最高，为17．19％；C2组腹水心脏指数（AHI）极显著高于C1组（P〈0．01），显著高于T1组（P〈0．05）；T1组血浆、心、肝和肺组织中超氧化物歧化酶（SOD）活性显著高于C2组（P〈0．05），同时T1组血浆、心、肝和肺组织中丙二醛（MDA）含量显著低于C2组（P〈0．05）。结论：饮水中添加真武汤口服液，能提高机体抗氧化能力，改善血液组织中的理化参数，提高机体抗冷应激能力，明显降低腹水综合征的发生。

256 Avian broiler chickens were randomly divided into four groups at 15 days of age, the normal group （group C1 ） was reared on normal ambient temperature （18 -22 ℃ ） , the model group （group C2 ） and the prevention groups （group T1 , group T2 ） were reared on low ambient temperature （8 - 12 ℃ ）. The group C1 and group C2 drinked water without additives. During a period of 20 days, the drinking water in group TI group T2 was added with 0. 8 mL· kg^-1 Zhen-Wu-Tang oral liquids. Vitamins in the formula of 0. 5 g ·^-1 Vc and 0. 1 g · 1^-1 VE were added in a preventive dose for observing the effects of Zhen-Wu-Tang oral liquid on the formation of ascites syndrome （AS） by the low ambient temperature. The results were as follows： During the experiment, the incidence of AS in group T1 （3. 13% ） , group T2 （6. 25%） and group C1 （3. 13%） were lower than that in group C2 （17.19%） （P〈0.01, P〈0.05）; The AHI of broilers in group C2 were higher than that in the group C~ and group T1 （P 〈0.01, P 〈0. 05） ; The SOD activites or MDA contents in the plasma and major tissues （ heart, liver, lung） of group T1 were higher or lower than those in the model group （ P 〈0. 05 ）. All the above results showed that ZhenWu-Tang oral liquid was the better prescription for preventing AS in broiler chickens. Its preventive effect may lie in the mechanism that it ad- justed the body fluid metabolism of internal organs, increased antioxidant function, ameliorated many hematological and biochemical parameters, improved the cold-stress-resistance of broiler chickens and thus prevented the AS.