咳喘闻剂对鼠血脂、肝脂和血糖的影响

Effect of Kechuan Inhalation on Bloodfat, Liver-fat and Blood-sugar in Rat and Mouse

为探讨咳喘闻剂治疗呼吸系统疾病的药理作用机制，本文初步观察了咳喘闻剂对大小鼠血脂、肝脂和血糖的影响。结果发现，吸入咳喘闻剂的芳香气味。能使小鼠高脂食料所致的血脂和肝脂程度下降；与此同时。也能使正常鼠肝脏中甘油三酯蓄积的程度减缓，增加肝糖原的合成。在降低正常鼠肝脏中甘油三酯的蓄积程度方面，在吸入芳香药气的同时，佐以药气溶液灌胃，效果更加显著。结果提示，咳喘闻剂具有一定的降血脂和护肝作用。

To investigate pharmacological mechanism of Kechuan inhalation(KCI),the effcts of Kechuan inhalation on blood-fat,liver-fat and blood-sugar in the rats and the mice were studied in this paper. The results showed that after inhaling drug-gas of Kechuan inhalation,the level of serum triglyceride and total cholesterol were decreased considerably in mice,at the same time,the increase of triglyceride induced by high lipid diet in liver of mice were inhibited significantly.In addition,the level fatty liver of hepatic homogenization triglyceride in rats with induced by DL-ethionine was lowered obviously by inhaling drug-gas of Kechuan inhalation. These results suggest that Kechuan inhalation maybe a role of reducing blood-fat and pretecting liver.