胸腹水中的乳酸脱氢酶和乳酸脱氢酶／白细胞比值测定的临床意义

Clinical Differential Diagnostic Value of LDH and LDH/WBC in Benign and Malignant Hydrothorax and Hydroperitonenm

目的 探讨胸腹水中乳酸脱氢酶（LDH）和乳酸脱氢酶／白细胞比值测定的临床鉴别诊断意义。方法 采用乳酸法检测73例患者不同性质胸腹水中的LDH和LDH／WBC比值，并对检测数据进行统计分析。结果 恶性肿瘤组和结核性胸膜炎组标本LDH差异无显著性（P〉0．05），但均高于慢性非特异性炎症组（P〈0．05）；恶性肿瘤组和结核性胸膜炎组的LDH／WBC比值差异无显著性（P〉0．05）；恶性肿瘤组和其他组的LDH／WBC比值差异无显著性（P〉0．05）。结论 检测LDH和LDH／WBC比值对鉴别胸腹水的性质无临床诊断意义。

Objective To explore the clinical differential diagnostic significance of lactate dehyrogenase （LDH） and LDH/WBC in benign and malignant hydrothorax and hydroperitoneum. Methods Lactic acid were used to determine the concentrations of LDH,count white blood cell （WBC） by microscope and proportion of LDH and WBC （LDH/WBC） in the hydrothorax and hydroperitoneum samples with different quality from 73 patients, respectively.the results were statistically analyzed. Results The LDH valuses in the samples from the malignant tumour patients and the tuberculous pleuritis patients did not show statistical difference （P〉0.05）, but higher than that from the chronic nonspecific inflammation patients （P〈0.05） ; the LDH/WBC in the samples from the malignant tumour patients and the tuberculous pleuritis patients did not show statistical difference （P〉0.05）; the LDH/WBC in the samples from the malignant tumour patients and the chronic nonspecific inflammation patients did not show statistical difference （P〉0.05）. Conclusion Quantitative detection of LDH and LDH/WBC can not show clinical reference value in differential diagnosis ofhydrothorax and hydroperitoneum quality.