摘要
目的探讨胃十二指肠疾病患者的生化变化规律。方法从胃肠激素、氧自由基和体液免疫等方面对患者进行同步观察。结果发现胃十二指肠患者胃泌素、胃动素和总羰基水平比正常人明显升高,IgG和IgM明显降低。并发现生长抑素与胰高血糖素之间呈负相关,IgG与IgA和IgM,IgA与IgM之间呈正相关。结论胃十二指肠疾病患者胃酸分泌增加,胃肠运动加快,体液免疫功能低下。
AIMS To study the biochemical changes in patients with gastroduodenal diseases. METHODS Gastrointestinal hormones, oxygen free base and humoral immunity were tested simultaneously. RESULTS Gastrin, motilin were significantly increased and IgG, IgM were significantly decreased in gastroduodenal patients. And somatostain was negatively correlated with glucagon, IgG was positively correlated with IgA and IgM, and IgA was positively correlated with IgM. CONCLUSIONS A increase of gastric acid secretion and gastrointestinal movement and a decrease of humoral immunity function are found in patients with gastroduodenal diseases.
关键词
胃疾病
十二指肠疾病
生化指标
stomach diseases duodenal diseases gastrointestinal hormones antibody formation
