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FHIT基因与胃癌的关系

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摘要 FHIT基因是定位于染色体3p14.2区域的一个候选抑癌基因,因含脆性位点FRA3B, 该基因具有不稳定性,其异常一般发生在与外界接触的器官上皮肿瘤中。胃癌是与环境致癌物密切相关的肿瘤,因而研究胃癌中FHIT基因的异常,对阐明胃癌的发生发展具有重要的理论基础和临床意义。现综述FHIT基因与胃癌关系的研究进展。
出处 《国际肿瘤学杂志》 CAS 2006年第6期438-440,共3页 Journal of International Oncology
基金 山东省自然科学基金资助项目(2004ZX05)
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