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Proteomics in colorectal cancer and hepatic metastasis research

Proteomics in colorectal cancer and hepatic metastasis research
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摘要 In the current post-genomic era, characterizing the function of genes is a major challenge. Proteomic researchers can translate genome information into useful biological insight. Colorectal cancer represents one of the most common malignancies worldwide. So it is applicable to compare and identify the differentially expressed proteins assiciated with colorectal cancer and hepatic metastasis. The identification of dlfferentially expressed protein would provide the basis for early diagnosis and detection, as well as clues for understanding the molecular mechanisms governing human colorectal carcinoma carcinogenesis, metastasis and progression, with the final goal to find better solutions to challenges in prevention of the colorectal liver metastasis and kill cancer cells with minimum toxicity maximally and specifically. In the current post-genomic era, characterizing the function of genes is a major challenge. Proteomic researchers can translate genome information into useful biological insight. Colorectal cancer represents one of the most common malignancies worldwide. So it is applicable to compare and identify the differentially expressed proteins associated with colorectal cancer and hepatic metastasis. The identification of differentially expressed protein would provide the basis for early diagnosis and detection, as well as clues for understanding the molecular mechanisms governing human colorectal carcinoma carcinogenesis, metastasis and progression, with the final goal to find better solutions to challenges in prevention of the colorectal liver metastasis and kill cancer cells with minimum toxicity maximally and specifically.
出处 《China Medical Abstracts》 2006年第1期82-87,共6页 中国医学文摘(外科学分册英文版)
关键词 colorectal cancer hepatic metastasis PROTEOMICS 结肠癌 直肠癌 肝移植 染色体
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参考文献10

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