恶性肿瘤患者焦虑情绪的调查分析

Investigation survey of anxiety in patients with malignant tumors

目的调查恶性肿瘤患者焦虑情绪的发生情况及对免疫功能的影响,探讨临床处理方法。方法应用汉密尔顿焦虑量表(HAMA)及Zung焦虑自评量表(SAS)对78例恶性肿瘤患者进行分析,同时检测其血液免疫指标。结果两种方法对恶性肿瘤患者焦虑情绪的诊断符合率为76．16%,近半数患者存在不同程度的焦虑情绪,其发生与年龄、疾病分期、经济负担等因素有关,下消化道肿瘤患者中发生焦虑情绪者明显多于上消化道肿瘤患者(P＜0．05),伴有焦虑情绪患者的免疫指标中CD3、CD4明显低于无焦虑情绪者(P＜0．01和＜0．05)。结论焦虑情绪在恶性肿瘤患者中的发生占一定比例,在消化道肿瘤患者中焦虑情绪的发生与原发肿瘤的部位有关,焦虑情绪可进一步抑制患者免疫功能,不利于恶性肿瘤患者的治疗和康复。

Objective To survey the anxiety of patients with malignant tumors with effects on immune function and to appraise the treatment method. Methods 78 patients with malignant tumors were analysed by HAMA and SAS methods, and compared the peripheral T lymphocytes and NK cells concomitantly. Results Anxiety occurred in approximately half of the patients with malignant tumors correlating with age, tumor stage, financial burden and location of tumor. In comparison with the patients without anxiety, the CD3 cells and the CD4 cells in patients with anxiety decreased significantly （P 〈 0.01 and P〈 0.05）. Conclusion Patients with malignant tumors have a high tendency of proportion in anxiety. Among the patients with alimentary tract tumors, anxiety correlates with the location of tumors and influences the body immune function, quality of life and treatment.