摘要
目的研究牛磺酸镁盐的制备工艺,以提高产物收率。方法以酸碱中和反应合成牛磺酸镁盐,采用正交试验对制备工艺进行优选。结果改进后最佳工艺条件:反应温度80℃;反应时间5h;牛磺酸与氢氧化镁投料摩尔比2∶1(氢氧化镁略过量)。结论该工艺合理,操作简便,收率可达55%。
OBJECTIVE To study the synthetic process of magnesium taurate salt for improving the production's yield. METHODS Magnesium tam:ate salt(MTS) was synthesized with the method of acid-alkali neutralizing reaction, and the optimum conditions of the synthesis process were selected by orthogonal experiment. RESULTS The optimimum conditions were as follows : the temperature of the synthesis was 80℃ ; the time of the synthesis was 5 hours; the salt was synthesized by reacting taurine and magnesium at a 2:1 molar ratio. CONCLUSION The optimum synthesis procedure is reliable, the operation is simple and the yield can reach 55%.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2006年第3期205-206,共2页
Chinese Journal of Modern Applied Pharmacy
关键词
牛磺酸镁盐
制备工艺
正交试验
magnesium taurate salt
synthetic process
orthogonal experiment