摘要
目的研究金翘感冒口服液的质量标准。方法对金翘感冒口服液中主要药物金银花、连翘、甘草进行薄层色谱鉴别；采用RP-HPLC法测定绿原酸的含量。结果薄层色谱检出绿原酸、连翘药材、甘草次酸特征斑点，绿原酸进样量在0．224—1．120μg线性关系良好，平均加样回收率99．81％，RSD为0．89％。结论方法简便易行，灵敏，结果准确，重现性好，可有效控制金翘感冒口服液的质量。
OBJECTIVE To study the quality standard of Jinqiao Ganmao Koufuye. METHODS TLC was applied to identify Flos Lontcerae Japonicae, Fructus Forsythiae and Radix et Rhizoma Glycyrrhizae in this prescription, and chlorogenic acid content in Kofuye was determined by RP-HPLC. RESULTS The characteristic maculae of chlorogenic acid ,Fructus Forsythiae and Glycyrrhetinic acid were detected by TLC. The linear rang of chlorogenic acid 0.224 - 1. 120μg, and the average recovery was 99.82% ,RSD = 2.3% （ n = 5 ）. CONCLUSION The evaluation methods are simple, sensitive, accurate and reproducible, and can be used for the quality control of this medicine.
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2006年第3期231-234,共4页
Chinese Journal of Modern Applied Pharmacy
关键词
金银花
连翘
甘草
绿原酸
高效液相色谱法
Flos Lonicerae Japonicae
Fructus Forsythiae
Radix et Rhizoma Glycyrrhizae
Weeping forsythia, Licorice root
chlorogenic acid
RP-HPLC
