卡介苗素与玉屏风颗粒合用对咳嗽变异性哮喘患儿的免疫调节作用

The immunological effects of combined use of Bacillus Calmette Guerin and Yu-ping-feng for treatment of cough variance asthma in children

目的探讨卡介苗素(BCG)注射液和玉屏风颗粒治疗咳嗽变异性哮喘(CVA)患儿免疫指标变化。方法治疗组为60例咳嗽变异性哮喘患儿给予肌注卡介苗素和口服玉屏风颗粒治疗,对照组60例使用常规对症治疗,疗程3个月,观察用药前后免疫功能的变化。结果用药后血清IgA,IgG,CD8+明显增高,IgE,CD4+,CD4+/CD8+下降,差异有显著性。结论卡介苗素注射液、玉屏风颗粒具有改善免疫功能的作用,可用于治疗咳嗽变异性哮喘。

OBJECTIVE Analysis of the immunological effects of combined use of Bacillus Calmette Guerin （BCG） and Yu-ping-feng for treatment of cough variance asthma in children. METHODS BCG and Yu-ping-feng were used to treat 60 ease of CVA in treatment group, while the general treatment was performed in the control group. The change of immunity was observed. RESULTS In the treatment group, the level of IgA, IgG and CD8^＋ were increased ovbiously than those of the control group, while the level of IgE, CD4^＋ and CD4^＋/CD8^＋ were devreased markedly （P 〈 0.01 ）. CONCLUSION Combined use of BCG and Yu-ping-feng can improved immnuity, they can be apply to treat CVA.