硫酸镁联合硝苯地平治疗子痫前期重度的临床分析

A clinical study after preeclampsia syndrome therapy with magnesium sulfate and nifudipine

目的探讨硫酸镁联合硝苯地平治疗子痫前期重度的疗效及安全性。方法选择我院于2003-2004年，诊断为子痫前期重度并采用硫酸镁联合硝苯地平治疗方案的患者78例。考察治疗前后血压变化，水肿、蛋白尿及自觉症状的疗效评价，统计母婴出现不良反应情况。结果经治疗，78例患者的血压均有效的控制到了安全范围，水肿及自觉症状治愈缓解有效率大于70％，蛋白尿症状治愈缓解有效率约为25％，母婴未见明显的毒副反应。结论硫酸镁联合硝苯地平治疗子痫前期重度可以有效的缓解病情，引起毒副反应不明显，是一种相对安全有效的治疗方案。

OBJECTIVE To investigate the effectiveness and safety of magnesium sulfate and nifudipine in treating preeelampsia syndrome. METHODS 78 patients who had preeelampsia syandrome were selected within 2003 and 2004 in our hospital. After treating with magnesium sulfate and nifudipine, the ehanga of blood pressure and curative effect was investigated and the side effects were collected. RESULTS Symptoms of all patients were improved after the patients received magnesium sulfate and nifudipine, with effective rate of 70% in edema and 25% in albuminuria. The side effects were not observed in our study. CONCLUSION Magnesium sulfate and nifudipine are effective and safe in the treatment of preeelmpsia syndrome when they are applied together.