摘要
正常的妊娠维持为母体对胎儿的免疫耐受。HLA-G作为一种人类的主要组织相容性复合体,具有限多态性。HLA-G多态性与胚胎的早期发育、IVF妊娠结局、正常妊娠维持、多种妊娠相关疾病及妊娠并发症(如复发性流产、子痫前期)的发生发展密切相关。
Normal pregnancy depends on materno-fetal tolerance. Human leukocyte antigen (HLA) -G is the non-classical human major histocompatibility complex (MHC) , having limited polymorphism. HLA-G polymorphism may be related to embryo early development, IVF pregnancy outcome, normal pregnancy maintenance, and certain complications of pregnancy such as pre-eclampsia and recurrent spontaneous abortions (RSA).
出处
《国际病理科学与临床杂志》
CAS
2006年第3期259-262,共4页
Journal of International Pathology and Clinical Medicine