复方甘草酸苷对肝癌合并肝硬化患者术中肝功能的影响

Effect of Stronger Neo-Mioniphagen C on Liver Function for the Patients with Hepatocarcinoma Associ-ated with Cirrhosis

目的:探讨复方甘草酸苷对肝癌合并肝硬化患者肝切除术中肝功能的影响。方法:55例肝癌并肝硬化患者随机分为A、B组,A组手术切皮前静脉滴注复方甘草酸苷(1ml/kg),B组给予等量的生理盐水;术后第1、3、6d抽取外周静脉血检测肝功能指标,并对结果进行统计学处理。结果:A、B组术后第1、3d各项肝功能指标均高于术前,且A组低于B组(P<0.05);术后第6d2组患者肝功指标下降,组间比较无显著性差异。结论:复方甘草酸苷用于肝癌并肝硬化患者肝切除术中有护肝效应。

OBJECTIVE ：To evaluate the effect of Stronger Neo-Mioniphagen C（SNMC） on liver function of the patients with hepatoeareinoma associated with cirrhosis.METHODS： 55 patients with hepatoeareinoma associated with cirrhosis were allocated to 2 groups randomly,group A：before operation SNMC（1ml/kg） was dripped intravenously to the patients,group B： before surgery NS（1ml/kg） was administered.On the 1st,3rd,6th postoperative day, the index of liver function of the perivenous blood were analyzed statistically.RESULTS：On the 1st,3rd postoperative day,all the value of liver function in both group is higher than the basic, and the value in group A is lower than that in group B（P〈0.05） .On the 6th postoperative day, the value of liver function in both groups decreased and had no significant difference between them.CONCLUSIONS： SNMC has protective effect on liver function for the patients with hepatoeareinoma associated with cirrhosis.