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宫颈癌组织中人乳头瘤病毒以及单纯疱疹病毒感染的检测 被引量:3

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摘要 目的研究人乳头瘤病毒(HPV)以及单纯疱疹病毒(HSV)以及HPV各型别在宫颈癌变中的作用。方法采用PCR方法对宫颈癌和正常宫颈组织HPV、HSV的DNA进行检测,并应用限制性内切酶片段长度多态性方法对HPVDNA进行分型。结果宫颈癌标本HPV的检出率为58.33%,正常宫颈组织标本HPV检出率10.71%。宫颈癌组织中检测到的HPV型别以HPV16、HPV18为主。宫颈癌组织标本中HSV检出率28.33%,正常宫颈组织标本7.14%。宫颈癌组织标本中,HSV与HPV感染可能有相关性。结论HPV感染与宫颈癌变有密切关系,以HPV16和HPV18为主。HSV可能作为HPV协同因子在宫颈癌变过程中发挥作用。
出处 《中国中西医结合皮肤性病学杂志》 CAS 2006年第2期93-94,共2页 Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine
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