D-二聚体测定在下肢深静脉血栓诊断中的临床价值

Clinical value of D-dimer testing in diagnosis of patients with deep vein thrombosis of the lower extremity

目的探讨D-二聚体(DD)测定在下肢深静脉血栓形成(DVT)诊断中的临床价值。方法回顾分析1 0 6例DVT患者DD值在不同的发病时间和临床分型的变化,并与9 9例下肢深静脉瓣膜功能不全(PDVI)患者DD值进行比较。结果DVT患者DD值在急性期内含量较高,陈旧性血栓随时间而逐步降低,而无血栓者呈阴性;周围型DVT阳性率高达8 5.7%。结论DD可作为急性DVT诊断、预测及预后判断方法之一,尤其对周围型DVT诊断更适合。

Objective To discuss the clinical value of D-dimer （DD） testing in diagnosis of patients with deep vein thrombosis （ DVT ） of the lower extremity. Methods An analysis retrospectively was made on the changes of DD testing in 106 cases of DVT at different periods after onset and different clinical stages of DVT, and DD testing in 99 patients with primary deep venous insufficiency （PDVI） as control group. Results DD was higher in the acute stage of DVT, and gradually decreased with time in chronic DVT, and was negative in the patients with PDVI ; the positive rate was up to 85.7 % in the distal DVT. Conclusions The DD testing can be used as one of the methods for diagnosis, prediction and prognosis of acute DVT, especially for diagnosis of distal DVT.