颅针与头针对急性脑梗死患者血清血管内皮生长因子影响的观察

Effect of skull acupuncture and scalp acupuncture on serum vascular endothelial growth factor in the patient of acute cerebral infarction

目的:探讨颅针与头针对急性脑梗死(CI)效应机制的差异。方法:分别采用单纯药物(A组)和针刺颅骨缝区(冠状缝、矢状缝、人字缝等)加药物(B组)、针刺标准化头针方案穴区(对侧顶颞前斜线、顶颞后斜线)加药物(C组)治疗急性CI患者各20例,对照观察患者血清血管内皮生长因子(VEGF)。结果:治疗前后A组血清VEGF含量变化差异无显著性意义(P>0·05),B组、C组血清VEGF含量升高差异显著(P<0·01,P<0·05),与A组比较差异有显著性意义(P<0·05),B组治疗后VEGF水平与C组比较差异无显著性意义(P>0·05)。结论:颅针加药物治疗对急性脑梗死血清内皮生长因子的影响与标准头针加药物治疗相当。

Objective To investigate effect of skull suture acupuncture （skull acupuncture） and scalp acupuncture on serum vascular endothelial growth factor （VEGF） in the patient of acute cerebral infarction （CI）. Methods Twenty cases of CI were treated with skull suture acupuncture at coronal suture, sagittal suture, lambdoid suture, etc. combined with medication （group B）, group C （n = 20） with scalp acupuncture at contralateral Dingnie Qianxiexian （MS 6） and Dingnie Houxiexian （MS 7） plus medication, and group A （n=20） with medication. Changes of serum VEGF contents were investigated in the three groups. Results After treatment, the serum VEGF content did not significantly change in group A （P〉0. 05）, and significantly increased in group B and group C （P〈0. 01, P〈0. 05）, with significant difference as group B and C compared with that of group A （P〈0. 05）, and with no significant difference between group B and group C （P〉0. 05）. Conclusion Skull suture acupuncture combined with medication and scalp acupuncture plus medication have a similar effect on serum VEGF in the patient of acute cerebral infarction.