1Lipinski CA, Lombardo F, Dominy BW, et al.Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings [J]. Adv Drug Deliv Rev, 1997,23:3 -25 .
2Lipinski CA, Lombardo F, Dominy BW, et al.Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings [J]. Adv Drug Deliv Rev,PⅡ, 2001,46:3 -26.
3Gardner CR, Almarsson O, Chen HM, et al. Application of high throughput technologies to drug substance and drug development [J]. Comp Chem Eng, 2004, 28:943 - 953.
4Gardner CR, Walsh CT, Almarsson O. Drug as materials: valuing physical form in drug discovery [J].Nat Rev Drug Discov, 2004,3:926- 934.
5Morissette SL, Almarsson O, Peterson ML, et al. High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids [ J ]. Adv Drug Deliv Rev, 2004,56:275 - 300.
6Vippagunta SR, Brittain HG, Grant David JW.Crystalline solids [J]. Adv Drug Deliv Rev, 2001,48:3 - 26.
7Datta S, Grant David JW. Crystal structure of drugs:advances in determination, prediction and engineering[J]. Nat Rev Drug Discov, 2004,3:42-56.
8Amidon GL, Lennernas H, Shah VP. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability [J]. Pharm Res, 1995,12:413 - 420.
9Kerns EH. High throughput physicochemical profiling for drug discovery [ J]. J Pharm Sci, 2001 , 90:1838 -1858.
10Bevan CD, Lloyd RS. A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates [J]. Anal Chem, 2000,72 : 1781 - 1787.
6Tatyana Gershanik,Sharon Benzeno,Simon Benita. Interaction of a Self-Emulsifying Lipid Drug Delivery System with the Everted Rat Intestinal Mucosa as a Function of Droplet Size and Surface Charge[J] 1998,Pharmaceutical Research(6):863~869
7Panayiotis P. Constantinides. Lipid Microemulsions for Improving Drug Dissolution and Oral Absorption: Physical and Biopharmaceutical Aspects[J] 1995,Pharmaceutical Research(11):1561~1572