摘要
目的 了解上海市社区居民2型糖尿病、糖调节异常(IGR)患病率及其分布特征。方法 采用多阶段整群随机抽样方法,对上海市城、乡社区居民15-74岁者进行横断面的调查。结果 上海市居民2型糖尿病、糖耐量低减(IGT)和空腹血糖受损(IFG)患病率分别为8.6%(1000/11589)、6.9%(802/11589)和1.0%(120/11589)(标化率为6.2%、5.1%和0.8%)。超重、肥胖人群中2型糖尿病患病率为11.5%(454/3946)和16.3%(207/1273),IGT患病率为8.9%(352/3946)和12.0%(153/1273),IFG患病率为1.4%(57/3946)和2.3%(29/1273),明显高于体质指数正常人群[分别为5.3%(337/6364),4.6%(294/6364),0.5%(34/6364)](均P〈0.01)。中心性肥胖人群中2型糖尿病患病率为16.5%(525/3173),IGT患病率为11.7%(372/3173),IFG患病率为1.6%(52/3173),明显高于无中心性肥胖人群[分别为5.6%(475/8416),5.1%(430/8416),0.8%(68/8416)](均P〈0.01)。高血压人群中2型糖尿病患病率为17.4%(479/2752)、IGT患病率为11.0%(303/2752)、IFG患病率为2.0%(56/2752),明显高于无高血压人群[分别为5.9%(521/8837),5.6%(499/8837),0.7%(64/8837)](均P〈0.01)。男性2型糖尿病、IGT和IFG患病率分别为8.9%(412/4621)、6.4%(296/4621)和1.0%(47/4621),女性2型糖尿病、IGT和IFG患病率分别为8.4%(588/6968)、7.3%(506/6968)和1.0%(73/6968),2型糖尿病、IGT和IFG患病率在男女之间差异无统计学意义(均P〉0.05)。城市2型糖尿病、IGT和IFG患病率分别为11.2%(730/6500)、6.4%(419/6500)和1.2%(77/6500)(标化率分别为6.5%、4.9%和0.8%),农村2型糖尿病、IGT和IFG患病率分别为5.3%(270/5089)、7.5%(383/5089)和0.8%(43/5089)(标化率分别为3.8%、5.4%和0.7%),城乡之间2型糖尿病和IGT患病率差异有统计学意义(P〈0.05),IFG患病率差异无统计学意义(P=0.073)。新诊断2型糖尿病比例为47.6%,其中农村为69.3%(187/270),明显高于城市[39.6%(289/730)](P〈0.01)。结论 上海市DM患病率呈快速增长趋势,应注重对富裕起来的农村地区居民的早期2型糖尿病筛查。
Objective To investigate the prevalence of type 2 diabetes and impaired glucose regulation among the permanent urban and rural inhabitants in Shanghai. Methods Questionnaire survey, physical examination, and laboratory testing were conducted among 14401 urban and rural inhabitants aged 15 -74 in Shanghai selected by multistage cluster random sampling. The data about the prevalence of type 2 diabetes and impaired glucose regulation were collected and analyzed. Results The respondent rate of this investigation was 80.5% ( 11 589/14 401 ). The prevalence rates of type 2 diabetes, impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) were 8.6% ( 1000/11 589), 6.9% ( 802/11 589), and 1.0% (120/11 589) respectively (the standardized rates were 6.2%, 5. 1% and 0. 8% ). The prevalence rates of type 2 diabetes, IGT, and IFG were significantly higher in those with overweight,obesity, central obesity, and hypertension. The prevalence rates of type 2 diabetes, IGT, and IFG in men were 8.9% (412/4621), 6.4% (296/4621), and 1.0% (47/4621) respectively, all not significantly different from those of the women, i.e. e., 8.4% (588/6968), 7. 3% (506/6968), and 1.0% (73/6968) respectively ( all P 〉 0.05 ). The prevalence rates of type 2 diabetes and IGT in the urban area were 11.2% (730/6500) and 6.4% (419/6500) respectively, beth significantly higher than those in the rural area, i. e., 5. 3% (270/5089) and 7.5% (383/5089) respectively (both P 〈 0. 05). The prevalence rate of IFG in the urban area was 1.2% (77/6500), not significantly different from that in the rural area (0.8%, 43/5039, P 〉0.05). The prevalence of type 2 diabetes, IGT, and IFG increased apparently with age, body mass index, waist hip ratio, and waist circumference. The ratios of undiagnosed type 2 diabetes in the urban area and rural area were 39. 6% ( 289/730 ) and 69. 3% ( 187/270 ) respectively ( χ^2 = 74.07, P 〈 0.01 ). Conclusion The prevalence rate of type 2 diabetes in Shanghai is higher than the mean national level and shows an increasing tendency. Screening of type 2 diabetes in rich rural areas should be emphasized.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2006年第24期1675-1680,共6页
National Medical Journal of China
基金
上海市医学发展基金资助项目(01ZD001)
关键词
糖尿病
非胰岛素依赖型
患病率
Diabetes mellitus, non-insulin-dependend
Prevalence