供者特异性HLA抗体在慢性移植物肾病中的作用
摘要
近年来的临床资料提示供者特异性HLA抗体(DSA)在慢性移植物肾病(CAN)的发病中起了重要作用,并提出“慢性体液性排斥反应”的概念,为CAN的诊断和治疗提供了一个新的思路。本文综述了DSA介导的免疫损伤导致CAN的研究进展。
出处
《国际泌尿系统杂志》
2006年第4期468-471,共4页
International Journal of Urology and Nephrology
参考文献22
-
1Cai J,Terasaki PI.Humoral theory of transplantation:mechanism,prevention,and treatment.Hum Immunol,2005,66:334-342.
-
2Salama AD,Delikouras A,Pusey CD,et al.Transplant accommodation in highly sensitized patient:a potential role for Bcl-xL and alloantibody.Am J Transplant,2001,1:260 -269.
-
3Jin YP,Jindra PT,Gong KW,et al.Anti-HLA class-I antibodies activate endothelial cells and promote chronic rejection.Transplantation,2005,79(3 suppl):19-21.
-
4Naji A,Deschaseaux F,Racadot E,et al.Induction of tissue factor expression on human umbilical vein endothelial cells by cell-specific HLA class Ⅰ antibody:preliminary data.Transplant Proc,2005,37:2892-2893.
-
5Terasaki PI,Ozawa M.Predicting kidney graft failure by HLA antibodies:a prospective trial.Am J Transplant,2004,4:438 -443.
-
6Terasaki PI.Humoral theory of transplantation.Am J Transplant,2003,3:665-673.
-
7Lee PC,Terasaki PI,Takemoto SK,et al.All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies.Transplantation,2002,74:1192-1194.
-
8Piazza A,Poggi E,Borrelli L,et al.Impact of donor-specific ant -ibodies on chronic rejection occurrence and graft loss in renal transplantation:posttransplant analysis using flow cytometric techniques.Transplantation,2001,71:1106-1112.
-
9Worthington JE,Martin S,Al-Husseini DM,et al.Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome.Transplantation,2003,75:1034-1040.
-
10Hourmant M,Cesbron-Gautier A,Terasaki PI,et al.Frequency and clinical implications of development of donor-specific and non -donor-specific HLA antibodies after kidney transplantation.J Am Soc Nephrol,2005,16:2804-2812.
-
1刘志宏,谭建明,胡志林,范昱,丁言德.肾移植术后供者特异性抗体对移植肾近期效果的影响[J].中华器官移植杂志,2003,24(6):356-358. 被引量:2
-
2小肠[J].国外科技资料目录(医药卫生),2002(9):60-60.
-
3陈建华,魏文宁,朱明光,邹萍.肾移植受者血清中抗供者特异性抗体检测及预测排斥反应的意义[J].临床检验杂志,2007,25(2):99-100. 被引量:3
-
4李可洲,沈文律,万云乐.经门静脉输注供者特异性血管内皮细胞诱导豚鼠一大鼠异种移植免疫耐受的实验研究[J].汕头大学医学院学报,1998,11(4):1-4.
-
5李沙丹,霍文谦,李黔生.外周血干细胞移植在亲属活体供肾移植中的应用[J].国外医学(移植与血液净化分册),2003,1(1):37-39.
-
6石炳毅,蔡明.抗体介导的体液性排斥反应的研究进展[J].解放军医学杂志,2008,33(1):1-5. 被引量:4
-
7刘秉乾,马腾骧,王广有.异种移植诱导免疫耐受策略的研究进展[J].国外医学(泌尿系统分册),2004,24(6):729-731.
-
8吴强,张建伟,张力超,周广臣.针对供者特异性HLA抗体对肾移植急性排斥的影响[J].中国输血杂志,2010,23(S1):107-107.
-
9陈卫国,王庆堂,王亮,杨航,周鹏,曹文峰,刘祥丹,李沙丹.供者特异性活化T细胞频度预测肾移植急性排斥反应[J].中国组织工程研究与临床康复,2011,15(31):5785-5788.
-
10赵虎,黄玉山,赖晓凤,吴琳,唐敏英,张美娜,李仁哲,林泳福,王庆华,谭建明.Luminex技术在肾移植供者特异性抗体检测中的应用[J].中华器官移植杂志,2016,37(9):572-575.