湖北省日本血吸虫病家庭聚集性研究

Research of familial aggregation of schistosomiasis japonica in Hubei Province

目的研究日本血吸虫病患病是否呈家庭聚集性。方法2001年湖北省日本血吸虫病抽样调查2210户家庭,其中有539例患有日本血吸虫病,分布在470个家庭。本研究针对该数据,采用负二项分布以及二项分布进行拟合,如果该数据服从负二项分布或不服从二项分布,则血吸虫病患病呈家庭聚集性。结果利用负二项分布和二项分布进行拟合,所得统计学检验P值分别为0.2801和0.0007,表明该数据服从负二项分布、不服从二项分布。结论血吸虫病患病呈家庭聚集性。

Objective To analyze familial aggregation of schistosomiasis japonica. Methods In 2001, 2210 families were sampled in Hubei sampling survey of schistosomiasis japonica. Among them there were 539 patients distributed in 470 families. The data is analyzed by fitting negative binomial distribution and binomial distribution. If the data follows negative binomial distribution or doesn＇t follow binomial distribution, then the infection of schistosomiasis japonica has a phenomenon of familial aggregation. Results P values for fitting negative binomial distribution and binomial distribution are respectively 0.2801 and 0.0007. Conclusion The infection of schistosomiasis japonica in Hubei province has a phenomenon of familial aggregation.