高血压与非高血压脑梗死患者的危险因素研究

Risk Factors of Cerebral Infarction in Hypertensive and Non-hypertensive Patients

目的:探讨高血压与非高血压脑梗死的危险因素、亚型和预后。方法:根据高血压病史将976例脑梗死患者分为高血压组(516例)和非高血压组(460例)。对危险因素、脑梗死亚型和预后进行单因素和多因素分析。结果:高血压组既往脑梗死史、腔隙性脑梗死和后循环梗死发生率明显高于非高血压组。非高血压组高龄、心血管病和糖尿病明显多于高血压组,差异有显著意义。结论:高血压、糖尿病、心血管病和高龄是脑梗死的主要危险因素,高血压是引起腔隙性脑梗死和后循环梗死的重要病因。

Objective： To discuss the risk factors, subtypes and prognosis of cerebral infarction in hypertensive and non-hypertensive patients. Methods： A total of 976 patients with cerebral infarction were divided into hypertension （n = 516） and non-hypertension （n = 460） according to their history of hypertension. Single and multiple factor analysis in the risk factors, subtypes of cerebral infarct, and prognosis were performed. Results： The incidence of previous cerebral infarction, lacunar infarction, and posterior circulation infarction in the hypertension group was significantly higher than those in the non-hypertension group. Advanced age, cardiovascular diseases, and diabetes mellitus in the non-hypertension group were significantly more frequent than those in the hypertension group, and there were significant difference. Conclusions： Hypertension, diabetes mellitus, cardiovascular diseases, and advanced age are the main risk factors of cerebral infarction. Hypertension is the major causes of lacunar infarction and posterior circulation infarction.