期刊文献+

急性冠脉综合征的研究现状

下载PDF
导出
摘要 急性冠脉综合征(acu te coronary syndrom es,ACS)是最常见的心血管系统疾病之一,包括不稳定性心绞痛(UA)、Q波型心肌梗死(QM I)和非Q波型心肌梗死(NQM I)及心源性猝死(CSD)。近年来,大量的基础研究发现其发病机理与不稳定斑块的破裂有密切关系,且与多种血清标志物密切相关。对其进行明确诊断及危险评估对临床治疗有重要指导意义。ACS的治疗包括手术治疗和非手术治疗,随着对ACS研究认识的深入,不断开发出一些新的治疗措施,如新型抗血栓药物及基因治疗等。本文就ACS的发病机制、诊断、血清标志物和治疗综述如下。
出处 《西部医学》 2006年第4期475-478,共4页 Medical Journal of West China
  • 相关文献

参考文献21

  • 1Toshima S;Hasegawa A;Kurabayashi M.Circulating oxidized low density lipoprotein levels:a biochemical risk marker for coronary heart disease,2000.
  • 2Tsutomu S;Hiroshi K;Yayoi T.Clinical significance of increased plasma concentration of macrophage colony-stimulating factor in patients with angina pectoris[J],2000(3).
  • 3McKaY RG."Ischemia-guided" versus "early invasive" strategies in the management of acute coronary syndrome/non ST-segment elevation myocardial infarction;the interventionalist's perspective,2003(zk).
  • 4ACE Inhibitor Myocardial Infarction Collaborative Group.Indications for ACE inhibitors in the early treatment of acute myocardial infarction:systematic overview of individual data from 100,000 patients in randomized trials,1998(22).
  • 5Wong GC;Giugliano RP;Antman EM.Use of low-molecular weight heparin in the management of acute coronary artery syndrome and percutaneous coronary intervention[J],2003(03).
  • 6杨振华,潘柏申,许俊堂.中华医学会检验学会文件心肌损伤标志物的应用准则[J].中华检验医学杂志,2002,25(3):185-189. 被引量:401
  • 7Rother E;Brandl R;Baker DL.Subtype-selective an tagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerosis plaques[J],2003(6).
  • 8Gil M;Zarebinski M;Olszewski R.Fibfinogen serum levels in patients with stable coronary artery.disease and acute coronary syndrome,2000(50).
  • 9Mulvihill NT;Foley JB.Inflammation in acute coronary syndromes[J],2002(03).
  • 10Lee H;Shi W;Tontonoz P.Role for perxisome proliferators-activated receptor alpha in oxidized phospholipidsinduced synthesis of monocyte chemotactic protein-l and interleukin-8 by endothelial cells,2000.

二级参考文献27

  • 1胡大一,顼志敏.不稳定性心绞痛溶栓治疗的评价[J].中华心血管病杂志,1996,24(3):165-166. 被引量:89
  • 2[1]Davies MJ. The pathophysiology of acute coronary syndrome [J]. Heart ,2000,83(3) :361~366
  • 3[2]Dupuis J. Mechanisms of acute coronary syndrome and the potential role of statins [J]. Atheroscler Suppl, 2001,2 (1) : 9~14
  • 4[3]Tiffang B R,Barrali R. Advance in the pharmacology of acute coronary syndrome, plateler inbibition[J]. Emerg Med Clin North Am,2000,18(4) :723~743
  • 5[5]Yerem Y,Joel BB,Arman A, et al. Unstable angina pectoris [J]. N Engl J Med,2000,342(2) :101~114
  • 6[8]Meyer BJ,Badimon JJ,James HC,et al. Dissolution of mural thrombus by specific thrombin inhibition with r-Hirudin[J].Circutation, 1998,97 (7): 681~ 685
  • 7David A H. Complex alterations in gene expression occur in the knee ligaments of the skeletally mature multiparous rabbit during pregnancy. Biochemica Biophysica Acta, 1998, 1397:331-341.
  • 8Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature, 1993, 362:801-809.
  • 9Arderson T J, Uehata A, Gerhard M D, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol, 1995, 26(5):1235-1241.
  • 10Falk E, Shah P K, Fuster V. Coronary plaque disruption. Circulation, 1995, 92:657-661.

共引文献420

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部