伤痛贴的抗炎镇痛作用研究

Anti-inflammatory and analgesic effect of Shangtong tiemo

目的研究伤痛贴的抗炎镇痛作用。方法采用大鼠角叉菜胶性足跖肿胀、小鼠琼脂肉芽肿法观察伤痛贴的抗炎作用;采用大鼠局部伤口电刺激和大鼠辐射热甩尾法观察伤痛贴的镇痛作用。结果伤痛贴能有效地对抗小鼠琼脂肉芽肿作用,抑制大鼠角叉菜胶性足跖肿胀作用,对大鼠局部伤口电刺激和辐射热甩尾法致痛均有较强的镇痛作用。结论伤痛贴具有明显的抗炎、镇痛作用。

Aim To study the anti-inflammatory and analgesic effects of Shangtong tiemo. Methods Anti-inflammation effect of Shangtong tiemo was evaluated with the model of swelling in rat paw induced by carrageenin and granuloma in mice induced by agar. By using the pain model in rat induced by electricity irritation and radiation heat, the analgesic effect of Shangtong tiemo was investigated. Results Shangtong tiemo effectively reduced the degree of the swelling in rat paw and granuloma, which indicated its anti-inflammatory effect. It significantly inhibited the pain in rat induced by electricity irritation and radiation heat, which indicated its analgesic effect. Conclusion Shangtong tiemo has the obvious anti-inflammatory and analgesic effect.