复方抗类风湿胶囊药理学研究

Pharmacological study of compound kangleifengshi capsule

目的研究复方抗类风湿胶囊有无抗炎、镇痛作用。方法用佐剂性关节炎和多种炎症模型,观察本品的抗炎作用;以小鼠扭体法了解其镇痛作用。结果:本品对大鼠佐剂关节炎有显著的预防和治疗作用;对多种炎症模型有显著的抑制作用;对醋酸所致小鼠扭体反应有明显的镇痛作用。结论复方抗类风湿胶囊具有良好的抗炎、镇痛作用,对佐剂性关节炎具有明显的预防和治疗作用。

Aim To study the anti - inflammatory and analgetic actions of compound kangleifengshi capsules. Methods The anti-inflammatory action was observed by adjuvant arthritis and other inflammatory models. The analgetic effect was tested by sprain mice. Results The experiments proved that the capsule has significant preventing and treating effects on rat adjuvant arthritis,strong inhibition on many kinds of inflammatory models,and notable angalgetic action on sprain mice induced by acetic acid. Conclusion Compound kangleifengshi capsules has better anti-inflammatory and analgetic effects, can evidently inhibiting the primary affection of arthritis, and can antagonize the afresh swelling arthrosis.