心肌细胞凋亡的研究进展及意义

The Research Perspectives and Meaning of the Apoptosis of Cardiac Muscle Cells

心肌细胞凋亡是在一系列基因调控下进行的程序化细胞死亡,其实质是生理性细胞死亡。首先对心肌细胞调亡的研究方法、影响因素等方面进行了分析和总结;然后对心肌缺血、运动、心肌缺氧和心脏疾病与心肌细胞调亡等方面的研究进展进行了总结;并对心肌细胞凋亡的调节因素进行了初步探讨;最后对心肌细胞凋亡在心脏疾病和运动中的意义做了简短的总结和概括。

The apoptosis of cardiac muscle cells refers to an initiative cell death process that is controlled by a series of genes, and in fact it is a kind of physiological cell death. This article reviewed and analyzed the research methods and affecting factors of the apoptosis of cardiac muscle cells at first. Then we sum- marized the research progress of the apoptosis of cardiac muscle cells from aspects as follows, the blood lacking of cardiac muscle, and exercises, and the oxygen lacking of cardiac muscle, and the cardiac diseases, etc. And then we discuss the regulation factors. Finally, we summarized the meaning of the apoptosis of cardiac muscle cells in the areas of the cardiac diseases and exercises in brief.