单病种泌尿系医院感染危险因素对照研究

Risk Factors of Urological Hospital Infection among Patients with a Single Disease: A Control Study

目的 探讨不同单病种患者泌尿系医院感染特点及相关危险因素。方法 对2001年7月～2004年7月，临床确诊为泌尿系医院感染〉20例的单病种共219例，与同期随机抽取的219例未发生医院感染进行比较并进行单因素x^2检验分析。结果 均住院时间≥3周、使用抗感染药≥10d、留置导尿≥5d和各类侵人性操作，4种因素差异有非常显著性，均为泌尿系易感染的危险因素，抗感染药物使用不合理发生感染危险性概率最高。结论 泌尿系医院感染虽是多因素作用的结果，但是通过强化监控措施，重视正确合理使用抗感染药物，泌尿系医院感染是可以控制的。

OBJECTIVE To reveal the characteristics and the risk factors of urological hospital infection （UHI） among the patients with a single disease. METHODS Totally 219 cases with a single disease （every disease was suffered by 20 and more patients）, who suffered UHI from Jul 2001 to Jul 2004 were investigated as a test group, at the sametime the other 219 cases randomly selected without UHI were as a control group. The result was analyzed by single factor Zz test. RESULTS There were four risk factors for UHI with very significant differences between two groups. They were as follows., the time of hospitalization was 3 weeks and more, use of antimicrobials 10d and more, retention time of catheters 5 d and more and various aggressive manipulations were received. From them the unreasonable use of antibacterials was the main one. CONCLUSIONS UHI is emerged by many factors, but it could be controlled via strengthening the surveillance and control measures and emphasizing the reasonable use of antibacterials.