兔烧伤合并海水浸泡后重要器官的病理变化

Pathological Changes of Important Organs of Rabbits After Burn Injury with Seawater Immersion

观察兔烧伤合并海水浸泡后,皮肤、心、肝、脾、肺、肾组织病理学变化特点,为兔烧伤合并海水浸泡后的早期救治提供依据。新西兰兔20只,制作烧伤动物模型后,随机分为浸泡组(n=10)和对照组(不经海水浸泡组,n=10)。光镜和电镜下观察兔烧伤合并海水浸泡后,皮肤、心、肝、脾、肺、肾组织病理学变化特点,并用HP IA S-1000病理分析系统对肝细胞进行测量。结果显示,兔烧伤合并海水浸泡后,皮肤、心、肝、脾、肺、肾组织病理学变化明显比对照组严重,肝细胞体积明显小于对照组。兔烧伤合并海水浸泡后重要器官的病理变化有其自身特点,比其单纯烧伤后的病理变化明显加重。

The exoeriment was conducted to investigate the characteristics of pathological changes of skin,heart,liver,spleen,lung and kidney of rabbits after burn injury with seawater immersion. After burn injury, 20 New Zealand rabbits were divided randomly into immersion group（n= 10） and control group（without seawater immersion,n= 10）.＇The characteristics of pathological changes of skin ,heart, liver ,spleen ,lung ,and kidney after burn injury with seawater immersion were examined by light and electron microscopy. The changes of bepatocytes were measured with HPIAS-1000 pathological analysis system. The results showed that the pathological changes of skin,heart ,liver,spleen,lung and kidney of rabbits after burn injury with seawater immersion were more severe than those of control group. The volumes of hepatocytes of seawater immersion group were smaller than those of control group. The pathological changes of important organs of rabbits after burn injury with seawater immersion have unique characteristics,and are more severe than those of rabbits with burn injury alone.