减压阀植入术治疗难治性青光眼的远期疗效观察

Observation on the long-term effect of the ahmed glaucoma valve implantation on the refractory glaucoma

目的；观察青光眼减压阀植入手术治疗难治性青光眼的远期疗效。方法：应用青光眼减压阀植入手术治疗19例21眼难治性青光眼，术后随访5～8a，（平均6a），观察其临床疗效及其手术并发症。结果：本组远期成功率为53．3％；眼压由术前的（45．39±13．14）mmHg降至术后的（18．32±6．42）mmHg，差异有统计学意义（P〈0．01）。导致手术失败并发症为：引流盘周纤维包裹6眼（28．6％），引流管口堵塞2眼（9．5％），引流管暴露1眼（4．8％），角膜内皮失代偿1眼（4．8％）。结论：应用青光眼减压阀植入手术治疗难治性青光眼是一种相对有效、安全的治疗方法。

Objective： To observe the long-term effect of ahmed glaucoma valve （AGV） on the refractory glaucoma. Methods：After AGV implantation, a retrospective study of clinical effect and complication was conducted on 21 eyes from 19 patients with refractory glaucoma with follow-up period ranging from 60 to 96 months （mean 72 months）. Results：The long -term successful rate was 53.3%. The average IOP decreased from the preoperative （45.39±13.14） mmHg to the postoperative （18.32±6.42） mmHg, respectively, （P 〈0.01）. The complication caused by the unsuccessful operation included encapsulated bleb in 6 eyes （28.6%）,tube blockage in 2 eyes （9.5%）, exposure of tube in 1 eye （4.8%）, corneal de-compensation in 1 eye （4.8%）. Conclusion： The AGV implantation surgery may be effective and safe for treating refractory glaucoma.