用PCR法检测唾液腺组织中HHV－6DNA

Detection of Human Herpesvirus 6 (HHV 6) DNA by the Polymerase Chain Reaction (PCR) in Salivary Glands

采用多聚酶链反应（ＰＣＲ）的方法，首次对１８例国人唾液腺组织标本中人类疱疹病毒６型（ＨＨＶ６）特异ＤＮＡ序列进行了检测。结果腮腺组织８例阳性（８／９），颌下腺组织５例阳性（５／７），舌下腺组织１例阳性（１／２）。提示唾液腺可能是ＨＨＶ６的主要潜伏部位之一，唾液可能是该病毒的传播媒介。

To assess the presence of HHV 6 specific DNA in human salivary glands, eighteen specimens of salivary gland tissue were investigated using the polymerase chain reaction. Eight of nine parotid glands, five of seven submandibular glands and one of two sublingual glands showed positive. The findings suggest that salivary gland tissue is one of the potential sites for HHV 6 persistence following primary infection and saliva is a vehicle for transmission of the virus.