三阶梯止痛法治疗晚期癌痛62例临床分析

Three-step Ladder Approach to Analgesia for Pain in Patients with AdvancedCancer:A Clinical Analysis of 62 Cases

目的为了证实三阶梯止痛法的可行性和疗效。方法应用去痛片──强痛定─—盐酸二氢埃托啡（ｄｒｏｅｔｏｒｐｈｉｎｅ）组成的三阶梯止痛法治疗６２例晚期癌痛病人，按时定量口服给药。结果疼痛完全缓解２９例、部分缓解２５例、轻度缓解６例、无效２例。总有效率为９６．７７％（６０／６２）。副反应发生率为３３．８７％（２１／６２）。结论三阶梯止痛方法对绝大部分晚期癌症患者有止痛效果且副反应轻，可以耐受。

Objective To verify feasibility and ef-fect of three-step ladder approach to analesia.Method Three-step ladder apprach to analgesia,somedon─Ap237─dihydroetorphine hydrochlo-ride,was applied for the treatment of pain in 62 pa-tients with advanced cancer.The drugs were taken o-rally vvith fixed quantity at regular intervals.Results Twenty nine of the patients achieved complete re-mission,25 had partial remission,6 had slight remis-sion and 2 had no ren1ission. The total effective ratewas 96.77%(60/62).21 oL them(21/62)had sideeffects,being 33.87%,Coarlusions Three-step lad-der approach to analgesia can relieve pain of mostcancer patients and the side effects are tolerable.