注射用头孢唑肟钠治疗下呼吸道细菌感染的研究

Evaluation of the Efficacy of Ceftizoxime Sodium Intravenous Administration in Low Respiratory Tract Bacterial Infection

目的以益保世灵（注射用头孢唑肟钠，进口原料）为对照，评价注射用头孢唑肟钠（国产）治疗下呼吸道细菌感染的疗效和安全性。方法42例下呼吸道细菌感染患者随机分入观察组和对照组，观察组给予注射用头孢唑肟钠粉针剂（国产）治疗，对照组给予益保世灵治疗，疗程7～14天。结果观察组、对照组临床有效率分别为94．12％和84．21％，细菌清除率分别为85.71％和87．50％，结果无显著性差异（P〉0．05）。结论注射用头孢唑肟钠（国产）治疗下呼吸道细菌感染安全有效。

Object Evaluate the efficacy and the safety of ceftizoxime sodium intravenous administration（made in China） for treatment of low respiratory tract bacterial infection compared with Epocelin （injection with ceftizoxime sodium, imported raw materials）. Methods 42 cases of low respiratory tract bacterial infection patients randomly divided into two groups （observer group and control group）, the observer group was administrated ceftizoxime sodium （made in China） and control group was administrated Epocelin, regimens 7～14 days. Results The clinic efficacy of observer group and control group was 94.12% and 84.21%, the bacterial removal rate was 85.71% and 87.50%, respectively. The results showed that they had no significant differences （P 〉 0.05）. Conclusion Treatment low respiratory tract bacterial infections with ceftizoxime sodium intravenous administration （made in China） is safe and effective.