2Cui J,Holmes EH,Greene TG,et al.Oxidative DNA damage precedes DNA fragmentation after ixperimental stroke in rat brain.FASEB J,2000,14:955-967.
3Gaucia Ruiz C,Colell A,Mari M,et al,Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species.J Biol Chem,1997,272:11369-11377.
4Sandeep Raha,Brian H.Robinson.Mitochondria,oxygen free radicals,and apoptosis.American Journal of Medical Genetics,2001,106:62-70.
5Ikeda T,Xia YX,Kaneko M,et al.Effect of the free radical scavenger,3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186),on hypoxia-ischemia-induced brain injury in neonatal rats.Neurosci Lett,2002,329:33-36.
6Munenori T,Masato N,Maeng B,et al.Jin.A radical scavenger,Edaravone,protects canine kidneys from ischemia-reperfusion injury after 72 hours of cold preservation and autotransplantation.Transplantation,2005,80:213-221.
7Yasuoka N,Nakajima W,Ishida A,et al.Neuroprotection of edaravone on hypoxic-ischemic brain injury in neonatal rats.Dev Brain Res,2004,151:129 -139.
8Jesmin I Noor,Tomoaki I,Kenichi M,et al.Short-term administration of a new free radicalscavenger,Edaravone,is moreeffective than its long-term administration for the treatment of neonatal hypoxic-ischemic encephalopathy.Stroke,2005,36:2468-2474.