牙周炎患者的血脂、血糖水平分析

Blood lipids and glucose levels in patients with penodontitis

目的分析牙周炎对患者血糖和血脂水平的影响。方法对117例侵袭性牙周炎(AgP)患者、40例慢性牙周炎(CP)患者及37名牙周健康者,空腹抽取静脉血,检测血脂、血糖水平,比较3组之间的差异。结果AgP患者平均甘油三酯水平[(1．09±0．79)mmol／L]显著高于健康对照者[(0．94±0．28)mmol／L,P<0．05];CP和AgP患者的血糖水平[分别为(5．40±1．01)mmol／L和(5．07±0．66)mmoL／L]均高于健康对照者(4．62±0．64 mmol／L),P< 0．01;CP组的总胆固醇高于健康对照组,P<0．05;AgP组的重度位点百分比与总胆固醇呈正相关(r=0．25,P<0．01)。结论牙周炎可能会影响血糖和血脂的水平。

Objective To determine the serum levels of lipid and glucose in patients with periodontitis. Methods The patients with aggressive periodontitis（ AgP,n=117 ） and chronic periodontitis （CP,n =40） and healthy controls （n =37） were recruited. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including total cholesterol, triglycerides, and fasting glucose were analyzed by biochemical analyzer. Results The average serum levels of triglycerides and glucose of the patients with AgP [ （ 1.09±0. 79 ） mmol/L and （ 5.07±0. 66） mmol/L ] were both significantly higher than those of the control group [ （0. 94±0. 28） mmol/L and （4. 62±0. 64） mmol/L], P 〈0. 05. Higher serum levels of total cholesterol and glucose were also observed in patients with CP [（4.61±1.23）mmol/Land （5.40±1.01）mmol/L] compared with controls [（4.49±0.78）mmol/L and （4. 62±0. 64 ） mmol/L ], P 〈 0. 05. Serum level of total cholesterol in AgP group was positively associated with percentage of severe sites （ r = 0. 25, P 〈 0. 01 ）. Conclusions Patients with periedontitis may have altered serum lipid and glucose levels compared with controls.