纤维蛋白原和血尿酸含量与急性心肌梗死预后的相关性研究

Correlations between the prognosis and fibrinogen and serum uric acid in patients with acute myocardial infarction

目的探讨纤维蛋白原(fibrinogen,FIB)和血尿酸(serum uric acid,SUA)含量与急性心肌梗死(acute myocardial infarction,AMI)预后的相关性。方法86例AMI患者分为两组,其中急性ST段抬高心肌梗死(ST elevation acute myocardial infarction,STEMI)患者44例(A组),急性非ST段抬高心肌梗死(NSTEMI)患者42例(B组),同时选择45例正常体检者为对照组(C组),分别测定其FIB和SUA的含量,并分析二者与AMI预后的相互关系。结果AMI组FIB和SUA的含量明显高于对照组,差异具有统计学意义。结论AMI患者FIB和SUA的含量明显高于正常人,其含量的高低与发生AMI时的病情、梗死面积及预后呈明显正相关。

Objective To investigate the relationship between the prognosis and fibrinogen （FIB） and serum uric acid （SUA） in patients with acute myocardial infarction （AMI）. Methods Eight six patients with AMI were divided into two groups while group A included 44 patients with SIEMI and group B included 42 patients with NSTEMI. Forty five normal people who received physical examination at the same time were enrolled as the control group （Group C）. Comparison between the 3 groups were made in terms of FIB and of SUA levels. Results The levels of FIB and SUA in patients with AMI were significantly higher than that of the control group. Conclusion The levels of FIB and SUA in patients with AMI are significantly higher than that of normal people and are directly correlated with the size of the infarction area and the prognosis.