实时三维超声心动图评价高血压病左心室肥厚

Evaluation of left ventricular hypertrophy in patients with essential hypertension using real-time three-dimensional echocardiography

目的探讨实时三维超声心动图(RT3DE)评价高血压病左心室肥厚的可行性及准确性。方法应用RT3DE测量22例中老年女性(其中高血压病12例,健康志愿者10例)舒张末期左心室心肌质量,同时从10健康志愿者中抽取8例行心脏磁共振(CMRI)检查并定量舒张末期左心室心肌质量。结果所有研究对象均获得了具有清晰内、外膜边界的左心室三维图像;RT3DE测量高血压病组左心室心肌质量为(100.86±16.95)g,对照组为(87.12±11.35)g,二者间有统计学差异(P=0.04);对照组中抽取的8例健康志愿者左心室心肌质量RT3DE测值为(84.42±7.49)g,CMRI测值为(82.43±6.95)g,二者无统计学差异(P>0.05),且具有良好的相关性(r=0.83,P=0.01)。结论RT3DE是一种可行的、准确的评价高血压病左心室肥厚的新方法。

Objective To evaluate the feasibility and accuracy of real-time three-dimensional echocardiography （RT-3DE） in the estimation of left ventricular hypertrophy in patients with essential hypertension （EH）. Methods Twelve patients with EH and 10 normal control subjects were investigated. Left ventricular mass （LVM） was obtained by RT-3DE in all the subjects. Moreover, 8 patients draw out from the control group were estimated by cardiac magnetic resonance imaging. Resuits RT-3DE datasets with good endocardlal and epicardial contour were acquired in all subjects; Compared with the control group, LVM obtained by RT-3DE in EH were higher （P=0. 04）; Furthermore, in the 8 patients, LVM obtained by RT-3DE had no significant difference with cardiac MR imaging （P〉0.05） and correlated well with cardiac MR imaging （r=0. 83, P=0. 01）. Conclusion RT-3DE is an accurate new technology in evaluation of left ventricular hypertrophy in essential hypertension.