抗磷脂综合征合并疣状心内膜炎误诊为亚急性细菌性心内膜炎1例报告并文献复习

Misdiagnosis of Antiphospholipid Syndrome Accompanied by Libman-Sacks Nonbacterial Endocarditis as Subacute Bacterial Endocarditis:One Case Report and Literature Review

目的:探讨疣状心内膜炎的误诊原因。方法:报告1例抗磷脂综合征合并疣状心内膜炎误诊为亚急性细菌性心内膜炎病例。结果:1例32岁女性患者因持续发热,血小板降低,体检发现心前区收缩期吹风样杂音,超声提示二尖瓣赘生物,CT发现多发性脑梗死误诊亚急性细菌性心内膜炎。结论:抗磷脂综合征多伴有血小板降低、多发性血栓形成及反复流产,可并发L ibm an-Sacks无菌性疣状心内膜炎。

Objective：To investigate the misdiagnostic causes of Libman-Sacks nonbacterial endocarditis. Methods：A case of antiphospholipid syndrome（APS） with Libman-Sacks nonbacterial endocarditis misdiagnosised as subacute bacterial endocarditis （SBE） was reported. Results：A female patient aged 32 was hospitalized with persistent fever, thrombocytopenia and was detected pericardial systolic murmur during physical examination, multiple cerebral infarction during CT scan as well as vegetation in mitral valve during echocardiography. Consequently she was misdiagnosed as SBE. Conclusions ： The clinical characteristics of APS are thrombocytopenia,recurrent spontaneous abortion and multiple thrombosis, and APS could be involved in cardiac valve and cause Libman-Sacks nonbacterial endocarditis.