微量血锌原卟啉测定在围产期中的应用

APPLICATION OF MEASUREMENT OF MICROBLOOD ZINCPROTOPOPHYRIN IN THE PERINATAL PERIOD

本文对我院产科门诊行产前检查的1124名健康孕妇进行了微量血锌原卟啉(ZPP)及血红蛋白(Hb)测定,同时.把两项均异常的孕妇409例随机分两组:治疗组108例、对照组301例。产后测定胎儿脐血ZPP,Hb值并分3组:正常组20例、治疗组23例、未治组25例。发现孕妇铁缺乏症发病率达40.2％,隐性缺铁3.8％。经补铁治疗贫血程度明显减轻,所生胎儿铁缺乏症明显减少,其差异非常显著(P<0.01)。因此,孕妇产前有效的补铁可预防婴儿铁缺乏症的发生,微量血ZPP测定可以做为孕期检查的敏感铁指标,值得推广。

In the present study prenatal examination was performed for 1124 healthy pregnant women in the obstetric clinic of our hospital to determine the amounts of zincprotoporphyrin (ZPP)and hemoglobin (Hb)which were off normal in 409 cases who were randomly divided into 2 groups:treatment-receiving group(108 cases )and control group(301 cases). Based on the postnatal valus meadured of ZPP and Hb in fetal cord blood were set up 3 groups : normal group (20 cases ), treatmentreceiving group (25 cases) and non-treatment-receiving group (25 cases). It was found that the iron deficiency incidence for the pregnant women reached 40. 2% and the latent iron deficiency incidence 3. 8%. Applying iron-supplementing therapy, anemic degrees were remarkably lessened and the occurrences of iron deficiency in neonates greatly reduced,which exist a signficant difference( P <0. 01). Therefor,effective prenatal supplementation of iron for pregnant women can prevent the occurrence of iron deficiency; measurement of microblood ZPP can be taken as a sensitive index of iron in prenatal examination, which is worthy of being spread.