摘要
为探索母乳PGE_2含量过高所致生理性腹泻与婴儿生长。发育及并发症的关系,本文对母乳PGE_2含量过高所致生理性腹泻88例进行了一年随访,其中治疗组43例,对照组45例,结果;1.母乳PGE_2含量过高所致生量性腹泻(简称生理性腹泻)对婴儿身长、体重无明显影响。2.生理性腹泻常见轻度、早期佝偻病,治疗组发病率为23.2％(10/43),对照组为35.5％(16/45),两者有显著性差异(P<0.01)。3.生理性腹泻可伴轻度营养性缺铁性贫血,两组血红蛋白分别为:96.5±5.3g/L与95.8±6.1g/L,其发病率治疗组为18.6％(8/43),对照组为31.1％(14/45),两者相比无差异(P<0.01)。4.腹泻时间长短与佝偻病和营养性贫血的发生有明显关系,腹泻时间>8周者两病发病率明显高于腹泻8周之内者(P<0.01)。故提出生理性腹泻不容忽视,在查明原因后应尽早治疗,以减少其并发症的发生。
A follow-up study of relation between physioldgical diarrhea caused by high level of PGE2 in mother's milk (mother's milk PGE2 diarrhea, MMPD) and infant growth and development was completed. (1)The MMPD had no effect on infant weight and height within one year. (2) The MMPD infant often suffered mild rickets (RC) and iron-deficiency anemia (IDA). Incidence rate (IR)in treated and control group were 23. 2%(10/43)and 35. 5%(16/45) in RC.18. 6%(8/ 43) and 31.1% (14/45) in IDA respectively. IR of RC and IDA releted to lasting time of MMPD. they were 43. 4%(20/46)and 39. 1%(18/46)when more then 8 weeks, 14. 2%(6/42)ahd 9. 5% (4/18) when less then 8 weeks respectively. So long-time MMPD should be treated,the key decreased complication was early treatment.
