我国14组中年人群血清胆固醇水平及分布特征

SERUM CHOLESTEROL LEVEL AND HYPERCHOLESTEROLEMIA PREVALENCE IN 14 CHINESE SAMPLE GROUPS

本研究目的在于了解９０年代初期我国中年人群血清胆固醇水平、分布特征及影响因素。研究对象选自不同地理位置、不同职业、不同经济状况的人群。地区包括东北、华北、华东、西南及华南，职业包括工人、农民、城市居民和渔民。危险因素调查人数共１５１６７人，年龄３５～６４岁。其中１４２５１人进行了血清总胆固醇测定，男性６５５２人，女性７６９９人。胆固醇测定由１２个协作单位的实验室完成，采用统一的标准化及质量控制方案。结果显示：不同人群血清胆固醇年龄调整均值，男性介于１５０．０～１９９．４ｍｇ／ｄｌ，女性介于１４６．１～１９８．２ｍｇ／ｄｌ；高血清胆固醇（ＴＣ≥２００ｍｇ／ｄｌ），年龄标化率，男性介于６％～４４％，女性介于５％～４２％。进一步分析表明，人群血清胆固醇水平在地域上无明显北高南低趋势，而是经济条件较好的大企业、大城市人群明显高于其它人群。高血清胆固醇检出率在部分人群中已处较高水平。

he prevalence of serum total cholesterol (TC) level and hypercholesterolemia (TC≥200mg/dl) was investigated among 14 sample groups from different geographical,occupational and economic status in China.14251 individuals (6552 Male,7699 female) aged 35￣59 were measured on serum total cholesterol by 12 laboratories which were following a common protocol for the serum collection,cholesterol assay and the quality control.The age adjusted mean of cholesterol was 150～199mg/dl in the men and 146￣198mg/dl in women.The rate of hypercholesterolemia incidence was 6%￣44% in the men and 5%￣42% in women,showing a distinct variation among the populations,and caused by the life style dietary pattern and economic status.