上海15～74岁居民代谢综合征的流行特征

Epidemiological feature of metabolic syndrome in Shanghai residents aged 15-74 years

目的了解上海15-74岁(中位年龄为50．00岁)居民代谢综合征的患病率及其分布特征。方法采用多阶段分层整群随机抽样方法,对上海14 327例15-74岁汉族人群进行横断面调查,计算代谢综合征及各组分患病率。代谢综合征的诊断分别按照国际糖尿病联盟(IDF)、美国国家胆固醇教育项目成人治疗组Ⅲ(ATPⅢ)和中华医学会糖尿病学分会(CDS)的定义。结果按照IDF标准,上海15-74岁居民代谢综合征的患病粗率为17．51％,年龄标化后为12．81％(95％CI: 12．26-13．36),女性高于男性(分别为14．79％、10．93％),城市高于农村(分别为13．71％、10．72％),并随年龄的增长而增加,45岁以上女性患病率明显上升。人群中同时具有3种以上代谢综合征异常组分数的个体比例高达22．28％。按照ATPⅢ标准,代谢综合征患病粗率为12．03％,年龄标化后为8．62％。按照CDS标准,代谢综合征患病粗率为13．98％,年龄标化后为10．41％。结论代谢综合征已成为影响上海城乡居民生命和健康的重大的公共卫生问题,应优先开展代谢综合征的社区综合防治。

Objective To assess the prevalence of the metabolic syndrome in Shanghai residents. Methods A cross-sectional study was conducted in Shanghai with a representative sample of 14 327 Chinese adults from 15 to 74 years of age. The sample was randomly selected using stratified cluster sampling. The criteria of International Diabetes Federation （IDF）, the US National Cholesterol Education Program Adult Treatment Panel Ⅲ （ATP Ⅲ） guidelines and the China Diabetes Society （CDS）, respectively, were applied for diagnosis. Results Diagnosed by using the IDF criterion, the crude prevalence of metabolic syndrome was 17. 51%, and the age and gender-adjusted prevalence was 12. 81% （95% CI： 12. 26 - 13. 36 ）. The prevalence of the metabolic syndrome was higher in females than in males （14. 79% and 10. 93%, respectively）, and higher in urban residents than in rural ones（ 13.71% and 10. 72%, respectively）. The age-specific prevalence of the metabolic syndrome increased in both male and female residents and the prevalence of metabolic syndrome in females 45 years of age or elder was significantly increased. The prevalence of having at least 3 parameters of metabolic syndrome was 22. 28%. According to the ATP Ⅲ guideline, the crude and age-adjusted prevalence of metabolic syndrome was 12.03% and 8.62%, respectively. Based on the criterion of CDS, they were 13.98% and 10. 41%. Conclusion There is a high prevalence of metabolic syndrome in Shanghai residents. Metabolic syndrome has become a noteworthy public health problem It suggests that community-integrated control of metabolic syndrome should have its priority.