期刊文献+

单甲脒包装工人心血管效应的观察 被引量:3

A STUDY ON THE CARDIOVASCULAR EFFECT OF BTS 27271 AMONG PACKERS
下载PDF
导出
摘要 对11名单甲脒包装女工作为期4个月的健康效应的前瞻定群调研。下午班后双手单甲脒污染量为6.38mg/cm2,尿中总浓度为0.414mg/L接触前为0.081mg/L;显著表现为头昏、嗜睡、乏力、皮疹、血压下降、心电图异常及尿中儿茶酚胺代谢产物VMA减少。累计接触水平与症状体征积分、血压降幅及尿VMA浓度间都存在接触-效应关系,提示脒类农药中毒的关键是心血管损害,系通过中枢儿茶酚胺α2受体的激动和对心肌直接损害所致。 A prospective cohort study on the cardiovascular effect of BTS 27271(halfmoiet of amitraz)among 11 women packers is reported.Exposure assessment was conducted with measurement of the hand contamination ,and biological monitoring the total urinary excretion of this chemical and metabolites.The main clinical manifestations were dizziness,somnolence,extreme fatigue,rashes,drop of blood pressure,abnormalities on EKG,and decrement of urinary VMA.Exposure effect relationship was demonstrated.The results suggested that the prominent mechanism of formamidines toxicity is agonizing the alpha 2 adrenal receptor and myocardium damage,which provide clue for improving diagnosis and treatment of intoxication with such chemicals.
出处 《劳动医学》 1996年第2期80-84,共5页
基金 国家教委博士点基金
关键词 单甲脒 包装工人 心血管效应 农药中毒 职业中毒 BTS 27271,Packer,Cardiovascular effect
  • 相关文献

同被引文献11

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部