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人体皮肤各类创伤区纤维连接蛋白免疫组织化学的研究 被引量：6

Immunohistochemical study on FN of different wound margins in human skin
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摘要 本文应用免疫组织化学ＰＡＰ法对人体皮肤的切创、枪弹创、挫伤、挫裂创进行了ＦＮ染色观察研究，发现不同类型的创伤，由于致伤条件不同，即使创伤所经历的时间相同，而不同创伤区ＦＮ阳性染色的宽度和深度并不一样。 Fibronection of wound margin in human incised wound, bullet wound, laceration, and contusions was observed with immunohistochemical PAP method. The result showed that the FN positive stained area is much different following different types of wound and injured conditions, even if at the same time.
作者 赵子琴 陈忆九 张其英 刘志萍
机构地区 上海医科大学法医病理教研室
出处 《法医学杂志》 CAS CSCD 1996年第2期67-68,共2页 Journal of Forensic Medicine
关键词 创伤 纤维连接蛋白 免疫组织化学 皮肤损伤 fibronectin immunohistochemistry incised wound laceration bullet wound contusions
分类号 R641.02 [医药卫生—外科学] R751 [医药卫生—皮肤病学与性病学]
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同被引文献57

  • 1赵子琴,张其英,陈忆九,顾云菊,沈蕾,李洪伟.对人和鼠腹部皮肤切创缘壁伤后不同时间纤维连接蛋白变化的研究[J].法医学杂志,1993,9(3):105-108. 被引量：9
  • 2[1]Petersen TE,Phogersen HC,Skorstengaard K,et al.Partial primary structure of bovine plasma fibronectin: Three types of internal homology[J]. Proc Natl Acad Sci,1983,80:137- 41.
  • 3[2]Kornblintt AR,Umezawa K,Vibe Pedersen K,et al. Primary structure of human fibronectin: differ ential splicing may generate at least 10 polypeptides from a single gene[J]. EMBO J,1985,4:1755- 59.
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  • 5[4]Hershberger RP, Culp LA, et al. Cell- type- specific expression of alternatively spliced human fibronetin Ⅲ CS mRNAS[J]. Mol Cell Biol,1990,10:662- 71.
  • 6[5]Gutman A, Kornblihtt AR,et al. Identification of a third region of cell - specific alternative splicing in human fibronectin mRNA [J]. Proc Natl Acad Sci.1998,84:7179- 82.
  • 7[6]Akiyama SK,Olden K,Yamada KM,et al.Fibronectin and integrins in invasion and metastasis[J].Cancer Metastasis Rev,1995,14(3):173- 89.
  • 8[7]Mould AP,Komoriya A,Yamada KM,et al.The CS5 Peptide is a second Site in the Ⅲ CS region of fibronectin recognized by the integrinα 4β 1[J].J Biol Chem,1991,266:3579- 85.
  • 9[8]Magnuson VL,Young M,Schattenberg DG,et al.The alternative splicing of fibronectin pre- mRNA is altered during aging and in response to growth factor [J].J Biol Chem,1991,266:14654- 62.
  • 10[9]Mould AP;Askati JA, Craig SE,et al. Integrin alpha4 beta1- mediated melanoma cell adhesion and migration on vascular cell adhesion molecule- 1(VACM- 1) and the alternatively spliced Ⅲ CS region of fibronectin[J]. J Biol Chem,1994, 269(44):27224- 30.

引证文献6

二级引证文献23

法医学杂志
1996年 第2期

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