病毒性心肌炎患儿血清心肌钙蛋白I检测阳性与时间的关系

Relationship between Detective Time for Serum Cardiac Troponin I and Their Positive Rate in Children with Viral Myocarditis

目的探讨病毒性心肌炎（VM）患儿血清心肌钙蛋白Ⅰ（cTnI）检测阳性与时间的关系。方法临床诊断为急性VM患儿21例，分别于入院后不同时间静脉采血，动态检测血清cTnI，并与35例正常对照组比较。结果正常对照组血清cTnI均阴性；VM患儿刚入院时阳性6例（28．6％），至入院后6、12、18、24、48、72h，10～14d分别为7例（33．3％）、8例（38．1％）、9例（42．9％）、9例（42．9％）、13例（61．9％）、4例（19％）。入院后48、72h cTnI累计阳性率分别较刚入院时和入院后10～14d有显著性差异（P均〈0．05）。结论对临床上拟诊VM发病不久患儿，通过不同时间段反复多次采血，能提高cTnI检出阳性率。

Objective To explore the relationship between detective time for serum cardiac troponin I（cTnl） and their positive rate in diagnosis of viral myocarditis（VM）. Methods Twenty - one cases of VM were designed as the test group. The serum cTnl were dynamically detected and compared with the normal control group. Results The serum cTnl were all negative in the normal control group,of 6 cases （28.6%） in the test group were positive when admission,of 7 cases（33.3%）,8 cases（38.1%）,9 cases（42.9%）, 13 cases （61.9%） and 4 cases（ 19% ） were positive 6,12,18,24,48,72 h and 10 to 14 days laters respectively. There were statistic signiflcances, compared the accumulative total positive rate of 48 h and 72 h after hospitalization with of emission and of 10 to 14 days after hospitalization, respectively. Conclusion Monitoring serum cTnI dynamically may increase the positive rate of cTnl for the suspected patients.